A novel imidazolium salt-supported Mukaiyama reagent (2-chloropyridinium salt) has been developed and explored as an efficient coupling agent for amide bond formation. The use of an ionic liquid-supported reagent enabled isolation of the amide products by simple extraction with organic solvents in high purity and avoiding column chromatography purification.
K. Pandey, M. K. Muthyala, S. Choudhary and A. Kumar, RSC Adv., 2015, 5, 13797 DOI: 10.1039/C4RA14856H
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