Issue 11, 2015

Continuous flow vortex fluidic synthesis of silica xerogel as a delivery vehicle for curcumin

Abstract

Sol–gel synthesis of silica xerogel at room temperature is effective using a vortex fluidic device operating under scalable continuous flow conditions, using only tetramethyl orthosilicate as the silica precursor and deionized water. The gelation time of the hydrogel can be as short as 3.5 hours depending on the concentration of the silica. This process is also effective in incorporating preformed sub-micron particles of curcumin, as an effective vehicle for bioavailability of this compound, which was shown by antimicrobial activity against Staphylococcus aureus.

Graphical abstract: Continuous flow vortex fluidic synthesis of silica xerogel as a delivery vehicle for curcumin

Supplementary files

Article information

Article type
Communication
Submitted
24 Nov 2014
Accepted
15 Dec 2014
First published
15 Dec 2014

RSC Adv., 2015,5, 7953-7958

Author version available

Continuous flow vortex fluidic synthesis of silica xerogel as a delivery vehicle for curcumin

C. L. Tong, U. H. Stroeher, M. H. Brown and C. L. Raston, RSC Adv., 2015, 5, 7953 DOI: 10.1039/C4RA15109G

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