Issue 27, 2015

A simple yet effective fluorescent probe for detecting and imaging mercury ions in cells

Abstract

We have synthesized rhodol hydrazide (RDH) as a simple fluorescent probe for detecting Hg2+. The probe can be applied in nontoxic solvents (EtOH and H2O). The probe has high selectivity and sensitivity to Hg2+ at pH 6–8. In addition, the probe has a superior capacity to resist interference from other ions. Both fluorescence intensity and absorbance have a linear relationship with the concentration of Hg2+, which ensured the precise detection of Hg2+. Furthermore, we have studied the intracellular Hg2+ imaging behavior of the probe on mammalian cells, which indicated that the probe can be applied to monitor Hg2+ within biological samples, especially in mammalian cells.

Graphical abstract: A simple yet effective fluorescent probe for detecting and imaging mercury ions in cells

Supplementary files

Article information

Article type
Paper
Submitted
12 Dec 2014
Accepted
06 Feb 2015
First published
06 Feb 2015

RSC Adv., 2015,5, 20634-20638

A simple yet effective fluorescent probe for detecting and imaging mercury ions in cells

Y. Zhang, Q. Wang, P. Su, F. Zhao, J. Huang and B. Zhao, RSC Adv., 2015, 5, 20634 DOI: 10.1039/C4RA16267F

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