Issue 24, 2014

Enhancing in vitro biocompatibility and corrosion protection of organic–inorganic hybrid sol–gel films with nanocrystalline hydroxyapatite

Abstract

Application of novel organic–inorganic hybrid sol–gel coatings containing dispersed hydroxyapatite (HAp) particles improves the biocompatibility, normal human osteoblast (NHOst) response in terms of osteoblast viability and adhesion of a Ti6Al4V alloy routinely used in medical implants. The incorporation of HAp particles additionally results in more effective barrier proprieties and improved corrosion protection of the Ti6Al4V alloy through higher degree of cross-linking in the organopolysiloxane matrix and enhanced film thickness.

Graphical abstract: Enhancing in vitro biocompatibility and corrosion protection of organic–inorganic hybrid sol–gel films with nanocrystalline hydroxyapatite

Article information

Article type
Paper
Submitted
31 Jan 2014
Accepted
25 Apr 2014
First published
25 Apr 2014
This article is Open Access
Creative Commons BY-NC license

J. Mater. Chem. B, 2014,2, 3886-3896

Author version available

Enhancing in vitro biocompatibility and corrosion protection of organic–inorganic hybrid sol–gel films with nanocrystalline hydroxyapatite

A. A. El hadad, V. Barranco, A. Jiménez-Morales, E. Peón, G. J. Hickman, C. C. Perry and J. C. Galván, J. Mater. Chem. B, 2014, 2, 3886 DOI: 10.1039/C4TB00173G

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