Issue 18, 2015

A colorimetric and near-infrared fluorescent turn-on probe for in vitro and in vivo detection of thiophenols

Abstract

A colorimetric and near-infrared fluorescent probe for thiophenols was developed. This new probe features remarkably large Stokes shift, and shows a rapid, highly selective and sensitive detection process for thiophenols with obvious colorimetric and near-infrared fluorescence turn-on responses. The detection limit of this probe for thiophenols was found to be 70 nM. In addition, this probe shows great potential for in vitro and in vivo detection of thiophenols, which was exampled by the successful application of this probe for quantitative detection of thiophenol in real water samples and fluorescence imaging of thiophenol in living cells and zebrafish.

Graphical abstract: A colorimetric and near-infrared fluorescent turn-on probe for in vitro and in vivo detection of thiophenols

Supplementary files

Article information

Article type
Paper
Submitted
29 Jun 2015
Accepted
19 Jul 2015
First published
22 Jul 2015

Anal. Methods, 2015,7, 7534-7539

Author version available

A colorimetric and near-infrared fluorescent turn-on probe for in vitro and in vivo detection of thiophenols

D. Yu, Q. Zhai, S. Yang and G. Feng, Anal. Methods, 2015, 7, 7534 DOI: 10.1039/C5AY01672J

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