Issue 28, 2015
From the journal:

Chemical Communications

An entry to vinylcyclopropane through palladium-catalyzed intramolecular cyclopropanation of alkenes with unstabilized allylic tosylhydrazones†

Yang Yang,a   Jinpeng Li,a   Biao Du,a   Changchun Yuan,a   Bo Liu*ab  and  Song Qin*a  

* Corresponding authors

a Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. China
E-mail: chembliu@scu.edu.cn
Fax: +86 28 8541 3712
Tel: +86 28 8541 3712

b State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, P. R. China

Abstract

A diastereoselective Pd-catalyzed intramolecular cyclopropanation of alkenes with unstabilized allylic tosylhydrazones was developed. This methodology provides an efficient entry toward synthesis of the bicyclo[3.1.0] hexane system with an exo-double bond, and sets the basis for future elaboration of more complex polycyclic motifs.

Graphical abstract: An entry to vinylcyclopropane through palladium-catalyzed intramolecular cyclopropanation of alkenes with unstabilized allylic tosylhydrazones

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5CC00235D
Article type
Communication
Submitted
10 Jan 2015
Accepted
02 Mar 2015
First published
03 Mar 2015

Chem. Commun., 2015,51, 6179-6182

Permissions

Request permissions

An entry to vinylcyclopropane through palladium-catalyzed intramolecular cyclopropanation of alkenes with unstabilized allylic tosylhydrazones

Y. Yang, J. Li, B. Du, C. Yuan, B. Liu and S. Qin, Chem. Commun., 2015, 51, 6179 DOI: 10.1039/C5CC00235D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements