Issue 18, 2015
From the journal:

Chemical Communications

Bioconjugated persistent luminescence nanoparticles for Föster resonance energy transfer immunoassay of prostate specific antigen in serum and cell extracts without in situ excitation†

Bo-Yue Wuab  and  Xiu-Ping Yan*a  

* Corresponding authors

a College of Chemistry, Research Center for Analytical Sciences, State Key Laboratory of Medicinal Chemical Biology (Nankai University), Tianjin Key Laboratory of Molecular Recognition and Biosensing, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Nankai University, 94 Weijin Road, Tianjin 30071, China
E-mail: xpyan@nankai.edu.cn
Fax: +86-22-23506075

b College of Laboratory Medicine, Tianjin Medical University, 1 Guangdong Road, Tianjin 300203, China

Abstract

A novel Föster resonance energy transfer (FRET) immunoassay based on persistent luminescence nanoparticles (PLNP) was established for prostate specific antigen (PSA) detection in serum and cell extracts without in situ excitation. The specific FRET behavior allows highly selective and sensitive ratiometric photoluminescent detection of PSA in biological samples.

Graphical abstract: Bioconjugated persistent luminescence nanoparticles for Föster resonance energy transfer immunoassay of prostate specific antigen in serum and cell extracts without in situ excitation

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Article information

DOI
https://doi.org/10.1039/C5CC00286A
Article type
Communication
Submitted
12 Jan 2015
Accepted
30 Jan 2015
First published
30 Jan 2015

Chem. Commun., 2015,51, 3903-3906

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Bioconjugated persistent luminescence nanoparticles for Föster resonance energy transfer immunoassay of prostate specific antigen in serum and cell extracts without in situ excitation

B. Wu and X. Yan, Chem. Commun., 2015, 51, 3903 DOI: 10.1039/C5CC00286A

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