Issue 27, 2015

Rh(iii)-catalyzed and alcohol-involved carbenoid C–H insertion into N-phenoxyacetamides using α-diazomalonates

Abstract

Here we report a new and mild Rh(III)-catalyzed and alcohol-involved carbenoid C–H insertion into N-phenoxyacetamides using α-diazomalonates. This reaction provided a straightforward way for installing both an α-quaternary carbon center and a free-OH moiety into the phenyl ring, thus giving access to useful 2-(2-hydroxyphenyl)-2-alkoxymalonates with good substrate/functional group tolerance.

Graphical abstract: Rh(iii)-catalyzed and alcohol-involved carbenoid C–H insertion into N-phenoxyacetamides using α-diazomalonates

Supplementary files

Article information

Article type
Communication
Submitted
14 Jan 2015
Accepted
04 Feb 2015
First published
05 Feb 2015

Chem. Commun., 2015,51, 5868-5871

Author version available

Rh(III)-catalyzed and alcohol-involved carbenoid C–H insertion into N-phenoxyacetamides using α-diazomalonates

J. Zhou, J. Shi, X. Liu, J. Jia, H. Song, H. E. Xu and W. Yi, Chem. Commun., 2015, 51, 5868 DOI: 10.1039/C5CC00354G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements