Issue 24, 2015
From the journal:

Chemical Communications

Cu-catalyzed asymmetric addition of sp2-hybridized zirconium nucleophiles to racemic allyl bromides†

Mireia Sideraa  and  Stephen P. Fletcher*a  

* Corresponding authors

a Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK
E-mail: stephen.fletcher@chem.ox.ac.uk
Tel: +44 (0)18652 75642

Abstract

Alkenylzirconium nucleophiles made in situ by the hydrozirconation of terminal alkynes undergo dynamic kinetic asymmetric allylic alkenylation with racemic allyl bromides to give enantioenriched products.

Graphical abstract: Cu-catalyzed asymmetric addition of sp2-hybridized zirconium nucleophiles to racemic allyl bromides

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5CC00421G
Article type
Communication
Submitted
15 Jan 2015
Accepted
13 Feb 2015
First published
23 Feb 2015

Chem. Commun., 2015,51, 5044-5047

Author version available

Download author version (PDF)

Permissions

Request permissions

Cu-catalyzed asymmetric addition of sp2-hybridized zirconium nucleophiles to racemic allyl bromides

M. Sidera and S. P. Fletcher, Chem. Commun., 2015, 51, 5044 DOI: 10.1039/C5CC00421G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements