Issue 31, 2015
From the journal:

Chemical Communications

A ratiometric fluorescent probe for in situ quantification of basal mitochondrial hypochlorite in cancer cells†

Ji-Ting Hou,a   Kun Li,*a   Jin Yang,a   Kang-Kang Yu,a   Ye-Xin Liao,a   Yu-Zhao Ran,a   Yan-Hong Liu,a   Xue-Dong Zhou*b  and  Xiao-Qi Yu*a  

* Corresponding authors

a Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry Sichuan University, 29, Wangjiang Road, Chengdu, Sichuan Province, P. R. China
E-mail: kli@scu.edu.cn, xqyu@scu.edu.cn

b State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, P. R. China
E-mail: zhouxd@scu.edu.cn

Abstract

A ratiometric fluorescent probe (RMClO-2) for ClO− based on the conjugate of coumarin–rhodamine was presented, which could sense ClO− with fast response (within 5 s), high sensitivity and excellent selectivity. More importantly, RMClO-2 is the first mitochondria-targeted ratiometric fluorescent probe to image exogenous and endogenous ClO−.

Graphical abstract: A ratiometric fluorescent probe for in situ quantification of basal mitochondrial hypochlorite in cancer cells

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5CC01217A
Article type
Communication
Submitted
09 Feb 2015
Accepted
03 Mar 2015
First published
05 Mar 2015

Chem. Commun., 2015,51, 6781-6784

Permissions

Request permissions

A ratiometric fluorescent probe for in situ quantification of basal mitochondrial hypochlorite in cancer cells

J. Hou, K. Li, J. Yang, K. Yu, Y. Liao, Y. Ran, Y. Liu, X. Zhou and X. Yu, Chem. Commun., 2015, 51, 6781 DOI: 10.1039/C5CC01217A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements