Issue 31, 2015

A single quantum dot-based biosensor for telomerase assay

Abstract

Telomerase is a promising biomarker and a therapeutic target due to its extensive expression in human tumors such as lung cancer and breast cancer. Here, we develop a single quantum dot (QD)-based biosensor for the sensitive detection of telomerase activity. This single QD-based biosensor has significant advantages of simplicity and high sensitivity, and it can be applied for the discrimination of tumor cells from normal cells as well as the screening of anticancer drugs.

Graphical abstract: A single quantum dot-based biosensor for telomerase assay

Supplementary files

Article information

Article type
Communication
Submitted
23 Feb 2015
Accepted
12 Mar 2015
First published
12 Mar 2015

Chem. Commun., 2015,51, 6808-6811

A single quantum dot-based biosensor for telomerase assay

G. Zhu, K. Yang and C. Zhang, Chem. Commun., 2015, 51, 6808 DOI: 10.1039/C5CC01600B

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