Issue 47, 2015
From the journal:

Chemical Communications

Elucidating the relationship between superoxide anion levels and lifespan using an enhanced two-photon fluorescence imaging probe†

Wen Zhang,a   Xin Wang,a   Ping Li,*a   Fang Huang,a   Hui Wang,a   Wei Zhanga  and  Bo Tang*a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of Fine Chemicals, Shandong Normal University, Jinan 250014, P. R. China
E-mail: tangb@sdnu.edu.cn

Abstract

We report a new reversible fluorescent two-photon (TP) probe (PY-CA) with high TP absorption cross section and pH-independent fluorescence response, which allow monitoring of O2˙− fluxes dynamically, selectively and sensitively. The imaging results indicate that O2˙− at high levels can shorten the life of Caenorhabditis elegans.

Graphical abstract: Elucidating the relationship between superoxide anion levels and lifespan using an enhanced two-photon fluorescence imaging probe

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Article information

DOI
https://doi.org/10.1039/C5CC01670C
Article type
Communication
Submitted
25 Feb 2015
Accepted
27 Apr 2015
First published
06 May 2015

Chem. Commun., 2015,51, 9710-9713

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Elucidating the relationship between superoxide anion levels and lifespan using an enhanced two-photon fluorescence imaging probe

W. Zhang, X. Wang, P. Li, F. Huang, H. Wang, W. Zhang and B. Tang, Chem. Commun., 2015, 51, 9710 DOI: 10.1039/C5CC01670C

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