Issue 47, 2015
From the journal:

Chemical Communications

Spiroboronate Si-rhodamine as a near-infrared probe for imaging lysosomes based on the reversible ring-opening process†

Weiwei Zhu,‡ab   Xiaoyun Chai,‡b   Baogang Wang,b   Yan Zou,b   Ting Wang,*b   Qingguo Menga  and  Qiuye Wub  

* Corresponding authors

a College of Pharmacy, Yantai University, Yantai, Shandong 264005, China

b Department of Organic Chemistry, College of Pharmacy, Second Military Medical University, Shanghai 200433, China
E-mail: wangting1983928@gmail.com

Abstract

A cyclic boronate structure was incorporated into Si-rhodamine to design a pH-activatable near-infrared (NIR) probe based on the reversible ring-opening process triggered by H+. The probe showed general suitability of specific labelling of acidic lysosomes and tracking their pH changes in living cells.

Graphical abstract: Spiroboronate Si-rhodamine as a near-infrared probe for imaging lysosomes based on the reversible ring-opening process

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Article information

DOI
https://doi.org/10.1039/C5CC02496J
Article type
Communication
Submitted
26 Mar 2015
Accepted
23 Apr 2015
First published
23 Apr 2015

Chem. Commun., 2015,51, 9608-9611

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Spiroboronate Si-rhodamine as a near-infrared probe for imaging lysosomes based on the reversible ring-opening process

W. Zhu, X. Chai, B. Wang, Y. Zou, T. Wang, Q. Meng and Q. Wu, Chem. Commun., 2015, 51, 9608 DOI: 10.1039/C5CC02496J

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