Issue 50, 2015
From the journal:

Chemical Communications

Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo†

Wei Zhang,a   Wei Liu,a   Ping Li,*a   Junqing kang,a   Jiaoyang Wang,a   Hui Wanga  and  Bo Tang*a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China
E-mail: tangb@sdnu.edu.cn

Abstract

Herein, we have developed a novel reversible two-photon fluorescent probe that is well suited for monitoring HOCl levels selectively and instantaneously. Results showed the reversible and instantaneous responses of the probe towards intracellular HOCl. Moreover, the probe was successfully applied to the imaging of the HOCl levels in zebrafish and mice via two-photon imaging.

Graphical abstract: Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo

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Article information

DOI
https://doi.org/10.1039/C5CC02537K
Article type
Communication
Submitted
27 Mar 2015
Accepted
12 May 2015
First published
12 May 2015

Chem. Commun., 2015,51, 10150-10153

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Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo

W. Zhang, W. Liu, P. Li, J. kang, J. Wang, H. Wang and B. Tang, Chem. Commun., 2015, 51, 10150 DOI: 10.1039/C5CC02537K

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