Issue 43, 2015

An in situ Raman spectroscopy-based microfluidic “lab-on-a-chip” platform for non-destructive and continuous characterization of Pseudomonas aeruginosa biofilms

Abstract

Pseudomonas aeruginosa biofilm was cultivated and characterized in a microfluidic “lab-on-a-chip” platform coupled with confocal Raman microscopy in a non-destructive manner. Biofilm formation could be quantified by this label-free platform and correlated well with confocal laser scanning microscopy. This Raman-microfluidic platform could also discriminate biofilms at different developmental stages.

Graphical abstract: An in situ Raman spectroscopy-based microfluidic “lab-on-a-chip” platform for non-destructive and continuous characterization of Pseudomonas aeruginosa biofilms

Supplementary files

Article information

Article type
Communication
Submitted
02 Apr 2015
Accepted
22 Apr 2015
First published
22 Apr 2015

Chem. Commun., 2015,51, 8966-8969

Author version available

An in situ Raman spectroscopy-based microfluidic “lab-on-a-chip” platform for non-destructive and continuous characterization of Pseudomonas aeruginosa biofilms

J. Feng, C. de la Fuente-Núñez, M. J. Trimble, J. Xu, R. E. W. Hancock and X. Lu, Chem. Commun., 2015, 51, 8966 DOI: 10.1039/C5CC02744F

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