A novel FeCl3 mediated formal [2+2] cycloaddition/ring opening cascade of o-keto-cinnamates was developed for the synthesis of indenones. The reaction tolerates a broad range of functional groups, including bromide, chloride, amide, acid and ester groups.
![Graphical abstract: FeCl3 mediated synthesis of substituted indenones by a formal [2+2] cycloaddition/ring opening cascade of o-keto-cinnamates](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C5CC03040D&imageInfo.ImageIdentifier.Year=2015)
D. H. Dethe and G. M. Murhade, Chem. Commun., 2015, 51, 10891 DOI: 10.1039/C5CC03040D
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