Issue 71, 2015
From the journal:

Chemical Communications

A red emitting mitochondria-targeted AIE probe as an indicator for membrane potential and mouse sperm activity†

Na Zhao,‡ab   Sijie Chen,‡bc   Yuning Hong ORCID logo bc  and  Ben Zhong Tang*bde  

* Corresponding authors

a School of Chemistry & Chemical Engineering, Shaanxi Normal University, 620 West Chang' an Avenue, Xi'an, P. R. China

b Department of Chemistry, Division of Biomedical Engineering, Institute for Advanced Study, Division of Life Science, State Key Laboratory of Molecular Neuroscience and Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China
E-mail: tangbenz@ust.hk

c School of Chemistry, The University of Melbourne, Parkville, Victoria 3010, Australia

d Joint Research Laboratory, Guangdong Innovative Research Team South China University of Technology, Guangzhou, China

e HKUST Shenzhen Research Institute, No. 9 Yuexing First RD, South Area, Hi-tech Park, Nanshan, Shenzhen, China

Abstract

In this work, a red emission AIE active mitochondrial probe is developed. It is the first non-self-quenching mitochondria specific probe with membrane potential sensitivity. Its application in sensing the membrane potential differences in mouse sperm cells is demonstrated.

Graphical abstract: A red emitting mitochondria-targeted AIE probe as an indicator for membrane potential and mouse sperm activity

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Article information

DOI
https://doi.org/10.1039/C5CC04731E
Article type
Communication
Submitted
09 Jun 2015
Accepted
06 Jul 2015
First published
12 Aug 2015

Chem. Commun., 2015,51, 13599-13602

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A red emitting mitochondria-targeted AIE probe as an indicator for membrane potential and mouse sperm activity

N. Zhao, S. Chen, Y. Hong and B. Z. Tang, Chem. Commun., 2015, 51, 13599 DOI: 10.1039/C5CC04731E

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