Issue 75, 2015

Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode

Abstract

An electrochemical insulin-delivery system based on reduced graphene oxide impregnated with insulin is described. Upon application of a potential pulse of −0.8 V for 30 min, up to 70 ± 4% of human insulin was released into a physiological medium while preserving its biological activity.

Graphical abstract: Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode

Supplementary files

Article information

Article type
Communication
Submitted
08 Jul 2015
Accepted
30 Jul 2015
First published
30 Jul 2015

Chem. Commun., 2015,51, 14167-14170

Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode

F. Teodorescu, L. Rolland, V. Ramarao, A. Abderrahmani, D. Mandler, R. Boukherroub and S. Szunerits, Chem. Commun., 2015, 51, 14167 DOI: 10.1039/C5CC05539C

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