Issue 94, 2015

A high stiffness bio-inspired hydrogel from the combination of a poly(amido amine) dendrimer with DOPA

Abstract

A robust biodegradable hydrogel is constructed from two components containing G4.0 PAMAM and DOPA, which displays excellent interconnected porous 3D networks, higher mechanical strength, low and stable swelling and good biocompatibility. A mouse CSD model in vivo evidences that moderate bone-like tissue and extensive bony tissue are observed when the hydrogel is implanted.

Graphical abstract: A high stiffness bio-inspired hydrogel from the combination of a poly(amido amine) dendrimer with DOPA

Supplementary files

Article information

Article type
Communication
Submitted
08 Jul 2015
Accepted
21 Sep 2015
First published
21 Sep 2015

Chem. Commun., 2015,51, 16786-16789

Author version available

A high stiffness bio-inspired hydrogel from the combination of a poly(amido amine) dendrimer with DOPA

Y. Wang, Q. Zhao, Y. Luo, Z. Xu, H. Zhang, S. Yang, Y. Wei and X. Jia, Chem. Commun., 2015, 51, 16786 DOI: 10.1039/C5CC05643H

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