Issue 76, 2015
From the journal:

Chemical Communications

pH-Responsive supramolecular vesicles assembled by water-soluble pillar[5]arene and a BODIPY photosensitizer for chemo-photodynamic dual therapy†

Lu-Bo Meng,a   Wenyi Zhang,b   Dongqi Li,a   Yan Li,b   Xiao-Yu Hu,*a   Leyong Wang*a  and  Guigen Licd  

* Corresponding authors

a Key Laboratory of Mesoscopic Chemistry of MOE and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China
E-mail: lywang@nju.edu.cn, huxy@nju.edu.cn
Fax: +86-25-83597090
Tel: +86-25-83592529

b State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory of Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China

c Institute of Chemistry and BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China

d Department of Chemistry & Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061, USA

Abstract

Supramolecular vesicles which can successfully encapsulate DOX and exhibit rapid drug release in a low-pH environment are constructed based on the host–guest interaction of water-soluble pillar[5]arene and a BODIPY derivative. They show remarkable combination of chemo- and photodynamic activities, suggesting a promising drug nanocarrier.

Graphical abstract: pH-Responsive supramolecular vesicles assembled by water-soluble pillar[5]arene and a BODIPY photosensitizer for chemo-photodynamic dual therapy

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Article information

DOI
https://doi.org/10.1039/C5CC05785J
Article type
Communication
Submitted
13 Jul 2015
Accepted
04 Aug 2015
First published
04 Aug 2015

Chem. Commun., 2015,51, 14381-14384

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pH-Responsive supramolecular vesicles assembled by water-soluble pillar[5]arene and a BODIPY photosensitizer for chemo-photodynamic dual therapy

L. Meng, W. Zhang, D. Li, Y. Li, X. Hu, L. Wang and G. Li, Chem. Commun., 2015, 51, 14381 DOI: 10.1039/C5CC05785J

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