Issue 76, 2015

Highly selective two-photon imaging of cysteine in cancerous cells and tissues

Abstract

Abnormal concentrations of Cys have been reported to be implicated in various health problems, including cancer, neuropathy, and cardiomyopathy. We present a novel two-photon fluorescent probe for the specific recognition of cysteine over homocysteine and glutathione, and the bioapplication of this probe for the imaging of live cancerous cells and thick tissues.

Graphical abstract: Highly selective two-photon imaging of cysteine in cancerous cells and tissues

Supplementary files

Article information

Article type
Communication
Submitted
20 Jul 2015
Accepted
31 Jul 2015
First published
31 Jul 2015

Chem. Commun., 2015,51, 14401-14404

Author version available

Highly selective two-photon imaging of cysteine in cancerous cells and tissues

Y. H. Lee, W. X. Ren, J. Han, K. Sunwoo, J. Lim, J. Kim and J. S. Kim, Chem. Commun., 2015, 51, 14401 DOI: 10.1039/C5CC06038A

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