Issue 90, 2015

A fluorescent probe for H2S in vivo with fast response and high sensitivity

Abstract

In this work, we design and synthesize a new near-infrared (NIR) ratiometric fluorescent probe FD-H2S for the highly sensitive (DL 68.2 nM) detection of H2S with fast response (15 s), large emission shift (220 nm) and excellent enhancement (168-fold in ratiometric value). The probe could be applied for monitoring and imaging of exogenous or endogenous H2S in live MCF-7 cells and in live mice with the fastest response.

Graphical abstract: A fluorescent probe for H2S in vivo with fast response and high sensitivity

Supplementary files

Article information

Article type
Communication
Submitted
07 Aug 2015
Accepted
15 Sep 2015
First published
15 Sep 2015

Chem. Commun., 2015,51, 16225-16228

Author version available

A fluorescent probe for H2S in vivo with fast response and high sensitivity

H. D. Li, Q. C. Yao, J. L. Fan, N. Jiang, J. Y. Wang, J. Xia and X. J. Peng, Chem. Commun., 2015, 51, 16225 DOI: 10.1039/C5CC06612C

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