Issue 99, 2015
From the journal:

Chemical Communications

DyNAvectors: dynamic constitutional vectors for adaptive DNA transfection†

Lilia Clima,a   Dragos Peptanariu,a   Mariana Pinteala,a   Adrian Salicb  and  Mihail Barboiu*c  

* Corresponding authors

a Petru Poni” Institute of Macromolecular Chemistry of Romanian Academy – 41A, Aleea Gr. Ghica Voda, Iasi, Romania

b Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA

c Adaptative Supramolecular Nanosystems Group, Institut Européen des Membranes, ENSCM/UMII/UMR-CNRS 5635, Pl. Eugène Bataillon, CC 047, 34095 Montpellier, Cedex 5, France
E-mail: mihail-dumitru.barboiu@univ-montp2.fr

Abstract

Dynamic constitutional frameworks, based on squalene, PEG and PEI components, reversibly connected to core centers, allow the efficient identification of adaptive vectors for good DNA transfection efficiency and are well tolerated by mammalian cells.

Graphical abstract: DyNAvectors: dynamic constitutional vectors for adaptive DNA transfection

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Article information

DOI
https://doi.org/10.1039/C5CC06715D
Article type
Communication
Submitted
10 Aug 2015
Accepted
07 Oct 2015
First published
07 Oct 2015

Chem. Commun., 2015,51, 17529-17531

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DyNAvectors: dynamic constitutional vectors for adaptive DNA transfection

L. Clima, D. Peptanariu, M. Pinteala, A. Salic and M. Barboiu, Chem. Commun., 2015, 51, 17529 DOI: 10.1039/C5CC06715D

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