Issue 11, 2016
From the journal:

Chemical Communications

Single point mutation detection in living cancer cells by far-red emitting PNA–FIT probes†

N. Kolevzon,‡a   D. Hashoul,‡a   S. Naik,a   A. Rubinsteina  and  E. Yavin*a  

* Corresponding authors

a The Institute for Drug Research, The School of Pharmacy, The Hebrew University of Jerusalem, Hadassah Ein-Kerem, Jerusalem 91120, Israel
E-mail: eylony@ekmd.huji.ac.il

Abstract

Peptide nucleic acid bis-quinoline conjugates are reported as attractive far-red emitting probes that detect mutated mRNA in living cells at SNP resolution.

Graphical abstract: Single point mutation detection in living cancer cells by far-red emitting PNA–FIT probes

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Article information

DOI
https://doi.org/10.1039/C5CC07502E
Article type
Communication
Submitted
07 Sep 2015
Accepted
15 Dec 2015
First published
15 Dec 2015

Chem. Commun., 2016,52, 2405-2407

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Single point mutation detection in living cancer cells by far-red emitting PNA–FIT probes

N. Kolevzon, D. Hashoul, S. Naik, A. Rubinstein and E. Yavin, Chem. Commun., 2016, 52, 2405 DOI: 10.1039/C5CC07502E

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