Issue 9, 2016

Selective hydrogenation of nitriles to primary amines catalyzed by a novel iron complex

Abstract

Hydrogenation of nitriles to primary amines constitutes an atom-efficient and environmentally benign synthetic reaction. Herein we present a novel complex based on earth-abundant iron, and its application in the catalytic homogeneous hydrogenation of (hetero)aromatic, benzylic, and aliphatic nitriles to selectively form primary amines.

Graphical abstract: Selective hydrogenation of nitriles to primary amines catalyzed by a novel iron complex

Supplementary files

Article information

Article type
Communication
Submitted
01 Oct 2015
Accepted
03 Dec 2015
First published
15 Dec 2015

Chem. Commun., 2016,52, 1812-1815

Selective hydrogenation of nitriles to primary amines catalyzed by a novel iron complex

S. Chakraborty, G. Leitus and D. Milstein, Chem. Commun., 2016, 52, 1812 DOI: 10.1039/C5CC08204H

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