Issue 15, 2016
From the journal:

Chemical Communications

A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples†

Dan-Dan Wang,a   Qiang Jin,a   Li-Wei Zou,a   Jie Hou,b   Xia Lv,a   Wei Lei,b   Hai-Ling Cheng,c   Guang-Bo Ge*a  and  Ling Yang*a  

* Corresponding authors

a Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China
E-mail: geguangbo@dicp.ac.cn, ylingdicp@gmail.com

b Dalian Medical University, Dalian, China

c Cancer Institute, The Second Hospital of Dalian Medical University, Dalian, China

Abstract

A highly selective and sensitive bioluminescent sensor (DME) for human carboxylesterase 1 (hCE1) has been developed and well characterized. DME could be used for real-time monitoring of hCE1 activities in complex biological samples and for bio-imaging of endogenous hCE1 in living cells.

Graphical abstract: A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples

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Article information

DOI
https://doi.org/10.1039/C5CC09874B
Article type
Communication
Submitted
30 Nov 2015
Accepted
05 Jan 2016
First published
05 Jan 2016

Chem. Commun., 2016,52, 3183-3186

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A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples

D. Wang, Q. Jin, L. Zou, J. Hou, X. Lv, W. Lei, H. Cheng, G. Ge and L. Yang, Chem. Commun., 2016, 52, 3183 DOI: 10.1039/C5CC09874B

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