Issue 18, 2016

Outstanding drug loading capacity by water stable microporous MOF: a potential drug carrier

Abstract

A robust, highly water stable (up to 3 weeks), microporous MOF, [Zn8(O)2(CDDB)6(DMF)4(H2O)] {where CDDB = 4,4′-(9-H carbazole-3,6-diyl)dibenzoic acid}, was synthesized based on an open N–H site by a solvothermal process and exhibited an outstanding loading capacity (around 53.3 wt%) and satisfactory release capability (64.9% and 81.9%) for 5-fluorouracil, constituting a negligible cytotoxicity effect.

Graphical abstract: Outstanding drug loading capacity by water stable microporous MOF: a potential drug carrier

Supplementary files

Article information

Article type
Communication
Submitted
02 Dec 2015
Accepted
25 Jan 2016
First published
25 Jan 2016

Chem. Commun., 2016,52, 3669-3672

Author version available

Outstanding drug loading capacity by water stable microporous MOF: a potential drug carrier

P. P. Bag, D. Wang, Z. Chen and R. Cao, Chem. Commun., 2016, 52, 3669 DOI: 10.1039/C5CC09925K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements