Issue 19, 2015

Interfacing proteins with graphitic nanomaterials: from spontaneous attraction to tailored assemblies

Abstract

This critical review aims at giving insights on the spontaneous tendency of proteins and their constitutive parts to adsorb on graphitic nanomaterials (GNMs) through non-covalent interactions occurring at their interfaces. Specifically, it focuses on the theoretical and experimental studies carried out to comprehend in depth the forces ruling the adsorption processes of proteins on fullerene, carbon nanotubes and graphene. In a systematic way the reader is guided through the most recent and representative examples describing at the atomistic level of detail the structural modalities and the chemico-physical principles through which amino acids, polypeptides and folded proteins interact with GNMs' surface, thereby taking into consideration the mutual effects of both protein structural complexity and nanomaterial topology. Based on their chemical and structural features, the study and understanding of the protein–nanomaterial interfaces can be exploited in the view of design and control the spontaneous formation of biologically-active hybrid materials for the development of new tailored applications in the field of sensing, nanomedicine and biochemistry.

Graphical abstract: Interfacing proteins with graphitic nanomaterials: from spontaneous attraction to tailored assemblies

Article information

Article type
Review Article
Submitted
03 Mar 2015
First published
03 Jul 2015

Chem. Soc. Rev., 2015,44, 6916-6953

Author version available

Interfacing proteins with graphitic nanomaterials: from spontaneous attraction to tailored assemblies

F. De Leo, A. Magistrato and D. Bonifazi, Chem. Soc. Rev., 2015, 44, 6916 DOI: 10.1039/C5CS00190K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements