Issue 3, 2016
From the journal:

Green Chemistry

Efficient pyrido[1,2-a]benzimidazole formation from 2-aminopyridines and cyclohexanones under metal-free conditions†

Yanjun Xie,a   Jun Wu,a   Xingzong Che,a   Ya Chen,a   Huawen Huanga  and  Guo-Jun Deng*ab  

* Corresponding authors

a Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China
E-mail: gjdeng@xtu.edu.cn
Fax: (+86)0731-5829-2251
Tel: (+86)0731-5829-8601

b Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China

Abstract

An efficient procedure for pyrido[1,2-a]benzimidazole preparation from 2-aminopyridines and cyclohexanones under metal-free conditions is described. Non-aromatic cyclohexanones were used as the aryl source via a dehydrogenation–aromatization process using molecular oxygen as the green oxidant.

Graphical abstract: Efficient pyrido[1,2-a]benzimidazole formation from 2-aminopyridines and cyclohexanones under metal-free conditions

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Article information

DOI
https://doi.org/10.1039/C5GC01978H
Article type
Communication
Submitted
23 Aug 2015
Accepted
09 Sep 2015
First published
10 Sep 2015

Green Chem., 2016,18, 667-671

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Efficient pyrido[1,2-a]benzimidazole formation from 2-aminopyridines and cyclohexanones under metal-free conditions

Y. Xie, J. Wu, X. Che, Y. Chen, H. Huang and G. Deng, Green Chem., 2016, 18, 667 DOI: 10.1039/C5GC01978H

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