Issue 30, 2015
From the journal:

Organic & Biomolecular Chemistry

Copper-mediated cyanation of indoles and electron-rich arenes using DMF as a single surrogate†

Lianpeng Zhang,a   Ping Lu*a  and  Yanguang Wang*a  

* Corresponding authors

a Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China
E-mail: pinglu@zju.edu.cn, orgwyg@zju.edu.cn

Abstract

The copper-mediated cyanation of indoles with DMF as a single surrogate has been realized. This approach could be applied for the cyanation of some electron-rich arenes and aryl aldehydes as well. Aryl aldehydes were demonstrated to be the key intermediates in the cascade process of cyanation of indoles and electron-rich arenes.

Graphical abstract: Copper-mediated cyanation of indoles and electron-rich arenes using DMF as a single surrogate

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Article information

DOI
https://doi.org/10.1039/C5OB01244A
Article type
Paper
Submitted
18 Jun 2015
Accepted
25 Jun 2015
First published
30 Jun 2015

Org. Biomol. Chem., 2015,13, 8322-8329

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Copper-mediated cyanation of indoles and electron-rich arenes using DMF as a single surrogate

L. Zhang, P. Lu and Y. Wang, Org. Biomol. Chem., 2015, 13, 8322 DOI: 10.1039/C5OB01244A

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