Issue 41, 2015
From the journal:

Organic & Biomolecular Chemistry

A recognition-mediated reaction drives amplification within a dynamic library†

Jan W. Sadownik‡a  and  Douglas Philp*a  

* Corresponding authors

a School of Chemistry and EaStCHEM, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK
E-mail: d.philp@st-andrews.ac.uk
Fax: +44 (0)1334 463808
Tel: +44 (0)1334 467264

Abstract

A single, appropriately designed, recognition event targets and transforms one of two reactive members of an exchanging pool of compounds through a recognition-mediated irreversible cycloaddition reaction, altering dramatically the final composition and kinetic behaviour of the dynamic library.

Graphical abstract: A recognition-mediated reaction drives amplification within a dynamic library

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Article information

DOI
https://doi.org/10.1039/C5OB01621E
Article type
Paper
Submitted
03 Aug 2015
Accepted
25 Aug 2015
First published
25 Aug 2015
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2015,13, 10392-10401

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A recognition-mediated reaction drives amplification within a dynamic library

J. W. Sadownik and D. Philp, Org. Biomol. Chem., 2015, 13, 10392 DOI: 10.1039/C5OB01621E

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