Issue 56, 2015

Cross dehydrogenative coupling (CDC) of aldehydes with N-hydroxyimides by visible light photoredox catalysis

Abstract

A photoinduced cross-dehydrogenative-coupling (CDC) reaction between aldehydes and N-hydroxyimides has been developed for the synthesis of ester derivatives. Using 2 mol% [Ru(bpy)3]Cl2 in dry acetonitrile at room temperature with an LED light bulb, we were able to synthesize N-hydroxyesters in good yields. The ester derivatives are very useful synthetic intermediates, which were transformed to amide and oxazole building blocks in excellent yields.

Graphical abstract: Cross dehydrogenative coupling (CDC) of aldehydes with N-hydroxyimides by visible light photoredox catalysis

Supplementary files

Article information

Article type
Communication
Submitted
01 Apr 2015
Accepted
08 May 2015
First published
12 May 2015

RSC Adv., 2015,5, 44928-44932

Cross dehydrogenative coupling (CDC) of aldehydes with N-hydroxyimides by visible light photoredox catalysis

M. Dinda, C. Bose, T. Ghosh and S. Maity, RSC Adv., 2015, 5, 44928 DOI: 10.1039/C5RA05719A

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