Issue 95, 2015

Fabrication of paper-based microfluidic analysis devices: a review

Abstract

When compared with conventional microfluidic chips made of glass and polymer substrates, paper-based microfluidic analysis devices (μPADs) possess many unique advantages, including low-cost, easy-to-fabricate, strong capillary action and good biological compatibility. In recent years, μPADs have attracted increased interest and attention, which has led to their rapid development. Thousands of literature reports regarding μPADs have been published and a variety of μPADs fabrication methods have been reported. This review focuses on the development of the fabrication methods of 2D and 3D μPADs since 2007. A summary of the advantages and disadvantages of these methods is provided with particular attention paid to the resolution and cost of each method. Suitable applications of each method are discussed. Also, some trends of μPADs are summarized.

Graphical abstract: Fabrication of paper-based microfluidic analysis devices: a review

Article information

Article type
Review Article
Submitted
17 May 2015
Accepted
04 Sep 2015
First published
07 Sep 2015

RSC Adv., 2015,5, 78109-78127

Fabrication of paper-based microfluidic analysis devices: a review

Y. He, Y. Wu, J. Fu and W. Wu, RSC Adv., 2015, 5, 78109 DOI: 10.1039/C5RA09188H

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