Size dependent magnetic hyperthermia of octahedral Fe3O4 nanoparticles

Abstract

Magnetic nanoparticle hyperthermia is promising as a cancer therapeutic treatment. Shape and size are two crucial factors for the magnetic hyperthermia performance of nanoparticles. In this work, octahedral Fe₃O₄ nanoparticles with different sizes are successfully synthesized and their magnetic hyperthermia performances are investigated systematically in a gel suspension. The results suggest a wide size range (43–98 nm) for high SAR values (up to 2629 W g⁻¹). The SAR values are verified by hysteresis loss measured in the gel suspension. This study demonstrates that octahedral Fe₃O₄ nanoparticles can serve as an excellent thermal seed for high performance magnetic hyperthermia cancer treatment.