Issue 22, 2016

A new avenue to the synthesis of highly substituted pyrroles: synthesis from N-propargylamines

Abstract

Pyrroles have attracted much attention due to their potential biological activities. Developing more efficient methods for the generation of pyrrole cores with unusual substitution patterns e.g. 2,4-disubstituted pyrroles is particularly interesting. This review gives an overview of new developments in the synthesis of highly substituted pyrroles from N-propargylamines in recent years.

Graphical abstract: A new avenue to the synthesis of highly substituted pyrroles: synthesis from N-propargylamines

Article information

Article type
Review Article
Submitted
06 Oct 2015
Accepted
24 Dec 2015
First published
05 Jan 2016

RSC Adv., 2016,6, 18619-18631

Author version available

A new avenue to the synthesis of highly substituted pyrroles: synthesis from N-propargylamines

E. Vessally, RSC Adv., 2016, 6, 18619 DOI: 10.1039/C5RA20706A

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