Issue 41, 2015
From the journal:

Journal of Materials Chemistry B

Electrical stimulation of human mesenchymal stem cells on biomineralized conducting polymers enhances their differentiation towards osteogenic outcomes†

John G. Hardy,*abc   Rushi C. Sukhavasi,b   David Aguilar, Jr.,b   Maria K. Villancio-Wolter,a   David J. Mouser,b   Sydney A. Geissler,ab   Lindsey Nguy,b   Jacqueline K. Chow,b   David L. Kaplan*c  and  Christine E. Schmidt*ab  

* Corresponding authors

a J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
E-mail: johnhardyuk@gmail.com, schmidt@bme.ufl.edu
Fax: +1-352-273-9221
Tel: +1-352-273-9222

b Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712, USA

c Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA
E-mail: david.kaplan@tufts.edu

Abstract

Tissue scaffolds allowing the behaviour of the cells that reside on them to be controlled are of particular interest for tissue engineering. Herein we describe biomineralized conducting polymer-based bone tissue scaffolds that facilitate the electrical stimulation of human mesenchymal stem cells, resulting in enhancement of their differentiation towards osteogenic outcomes.

Graphical abstract: Electrical stimulation of human mesenchymal stem cells on biomineralized conducting polymers enhances their differentiation towards osteogenic outcomes

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Article information

DOI
https://doi.org/10.1039/C5TB00714C
Article type
Communication
Submitted
17 Apr 2015
Accepted
15 Sep 2015
First published
23 Sep 2015
This article is Open Access
Creative Commons BY license

J. Mater. Chem. B, 2015,3, 8059-8064

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Electrical stimulation of human mesenchymal stem cells on biomineralized conducting polymers enhances their differentiation towards osteogenic outcomes

J. G. Hardy, R. C. Sukhavasi, D. Aguilar, M. K. Villancio-Wolter, D. J. Mouser, S. A. Geissler, L. Nguy, J. K. Chow, D. L. Kaplan and C. E. Schmidt, J. Mater. Chem. B, 2015, 3, 8059 DOI: 10.1039/C5TB00714C

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