Issue 67, 2016
From the journal:

Chemical Communications

Sensitive SERS detection of miRNA via enzyme-free DNA machine signal amplification†

Xiaoxiao Li,a   Sujuan Ye*a  and  Xiliang Luo*a  

* Corresponding authors

a Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China
E-mail: xiliangluo@qust.edu.cn, yesujuan@126.com
Fax: +86-532-84022990
Tel: +86-532-84022990

Abstract

In this work, an enzyme-free signal amplified detection platform is described for miRNA detection with a DNA fueled molecular machine. Coupling SERS technology with multiple amplification modes, this flexible biosensing system exhibits high sensitivity and specificity.

Graphical abstract: Sensitive SERS detection of miRNA via enzyme-free DNA machine signal amplification

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Article information

DOI
https://doi.org/10.1039/C6CC04391G
Article type
Communication
Submitted
25 May 2016
Accepted
20 Jul 2016
First published
20 Jul 2016

Chem. Commun., 2016,52, 10269-10272

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Sensitive SERS detection of miRNA via enzyme-free DNA machine signal amplification

X. Li, S. Ye and X. Luo, Chem. Commun., 2016, 52, 10269 DOI: 10.1039/C6CC04391G

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