Issue 67, 2016
From the journal:

Chemical Communications

A TP-FRET-based two-photon fluorescent probe for ratiometric visualization of endogenous sulfur dioxide derivatives in mitochondria of living cells and tissues†

Xiaoguang Yang,‡a   Yibo Zhou,‡b   Xiufang Zhang,b   Sheng Yang,*a   Yun Chen,b   Jingru Guo,a   Xiaoxuan Li,a   Zhihe Qinga  and  Ronghua Yang*ab  

* Corresponding authors

a School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, China
E-mail: ysh1127@hnu.edu.cn, yangrh@pku.edu.cn
Fax: +86 731 88822523
Tel: +86 731 88822523

b State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China

Abstract

A ratiometric two-photon fluorescent probe for SO2 derivatives was first proposed based on acedan–merocyanine dyads via a TP-FRET strategy. It was successfully applied to visualization of the fluctuations of enzymatically generated SO2 derivatives in the mitochondria of HepG2 cells and rat liver tissues using two-photon fluorescence microscopy imaging.

Graphical abstract: A TP-FRET-based two-photon fluorescent probe for ratiometric visualization of endogenous sulfur dioxide derivatives in mitochondria of living cells and tissues

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Article information

DOI
https://doi.org/10.1039/C6CC05254A
Article type
Communication
Submitted
23 Jun 2016
Accepted
13 Jul 2016
First published
14 Jul 2016

Chem. Commun., 2016,52, 10289-10292

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A TP-FRET-based two-photon fluorescent probe for ratiometric visualization of endogenous sulfur dioxide derivatives in mitochondria of living cells and tissues

X. Yang, Y. Zhou, X. Zhang, S. Yang, Y. Chen, J. Guo, X. Li, Z. Qing and R. Yang, Chem. Commun., 2016, 52, 10289 DOI: 10.1039/C6CC05254A

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