Issue 88, 2016

Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

Abstract

A novel method for the introduction of a single protected amine-functional monomer at the chain end of RAFT polymers has been developed. This monomer addition, in concert with native chemical ligation, facilitated the development of a simple and versatile method for the end-functionalization of polymers with peptides.

Graphical abstract: Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

Supplementary files

Article information

Article type
Communication
Submitted
21 Jul 2016
Accepted
21 Sep 2016
First published
23 Sep 2016

Chem. Commun., 2016,52, 12952-12955

Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

N. Isahak, G. Gody, L. R. Malins, N. J. Mitchell, R. J. Payne and S. Perrier, Chem. Commun., 2016, 52, 12952 DOI: 10.1039/C6CC06010B

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