Issue 90, 2016

A macromolecular cyclometalated gold(iii) amphiphile displays long-lived emissive excited state in water: self-assembly and in vitro photo-toxicity

Abstract

We report an amphiphilic macromolecule containing a cyclometalated gold(III) complex that self-assembles into nano-sized micelles and also displays a long-lived emissive triplet excited state with a lifetime of 84 μs in degassed water. This amphiphilic AuIII complex exhibits good biocompatibility and activity towards in vitro photo-toxicity, as well as enhanced permeability and retention effects in vivo.

Graphical abstract: A macromolecular cyclometalated gold(iii) amphiphile displays long-lived emissive excited state in water: self-assembly and in vitro photo-toxicity

Supplementary files

Article information

Article type
Communication
Submitted
17 Aug 2016
Accepted
05 Oct 2016
First published
24 Oct 2016

Chem. Commun., 2016,52, 13273-13276

A macromolecular cyclometalated gold(III) amphiphile displays long-lived emissive excited state in water: self-assembly and in vitro photo-toxicity

F. Wang, M. Lan, W. To, K. Li, C. Lok, P. Wang and C. Che, Chem. Commun., 2016, 52, 13273 DOI: 10.1039/C6CC06767K

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