Issue 32, 2017

Fluorescent polymer prodrug nanoparticles with aggregation-induced emission (AIE) properties from nitroxide-mediated polymerization

Abstract

Aggregation-induced emission (AIE)-active polymer prodrug nanoparticles were readily prepared by growing short, well-defined polymer chains from an AIE dye by nitroxide-mediated polymerization, followed by co-nanoprecipitation of the resulting conjugates with similarly constructed anticancer polymer prodrugs. The nanoparticles had sharp fluorescence signal offering excellent imaging ability in living cells and their intra cellular localization to be accurately monitored.

Graphical abstract: Fluorescent polymer prodrug nanoparticles with aggregation-induced emission (AIE) properties from nitroxide-mediated polymerization

Supplementary files

Article information

Article type
Communication
Submitted
12 Nov 2016
Accepted
29 Mar 2017
First published
06 Apr 2017

Chem. Commun., 2017,53, 4489-4492

Fluorescent polymer prodrug nanoparticles with aggregation-induced emission (AIE) properties from nitroxide-mediated polymerization

Y. Bao, E. Guégain, V. Nicolas and J. Nicolas, Chem. Commun., 2017, 53, 4489 DOI: 10.1039/C6CC09052D

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