Issue 13, 2016

C–H carboxylation of heteroarenes with ambient CO2

Abstract

The C–H carboxylation of heteroarenes was achieved under transition metal-free reaction conditions with naturally abundant CO2 as the C1 source at relatively low temperature. The C–H carboxylation was mediated by KOt-Bu at atmospheric pressure of CO2, and thereby provided atom- and step-economical access to various heteroaromatic carboxylic acid derivatives.

Graphical abstract: C–H carboxylation of heteroarenes with ambient CO2

Supplementary files

Article information

Article type
Paper
Submitted
20 Jan 2016
Accepted
04 Apr 2016
First published
04 Apr 2016
This article is Open Access
Creative Commons BY license

Green Chem., 2016,18, 3804-3807

C–H carboxylation of heteroarenes with ambient CO2

S. Fenner and L. Ackermann, Green Chem., 2016, 18, 3804 DOI: 10.1039/C6GC00200E

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