Issue 17, 2016

Paper-based sensors and assays: a success of the engineering design and the convergence of knowledge areas

Abstract

This review shows the recent advances and state of the art in paper-based analytical devices (PADs) through the analysis of their integration with microfluidics and LOC micro- and nanotechnologies, electrochemical/optical detection and electronic devices as the convergence of various knowledge areas. The important role of the paper design/architecture in the improvement of the performance of sensor devices is discussed. The discussion is fundamentally based on μPADs as the new generation of paper-based (bio)sensors. Data about the scientific publication ranking of PADs, illustrating their increase as an experimental research topic in the past years, are supplied. In addition, an analysis of the simultaneous evolution of PADs in academic lab research and industrial commercialization highlighting the parallelism of the technological transfer from academia to industry is displayed. A general overview of the market behaviour, the leading industries in the sector and their commercialized devices is given. Finally, personal opinions of the authors about future perspectives and tendencies in the design and fabrication technology of PADs are disclosed.

Graphical abstract: Paper-based sensors and assays: a success of the engineering design and the convergence of knowledge areas

Article information

Article type
Tutorial Review
Submitted
07 Jun 2016
Accepted
28 Jun 2016
First published
28 Jun 2016

Lab Chip, 2016,16, 3150-3176

Paper-based sensors and assays: a success of the engineering design and the convergence of knowledge areas

A. M. López-Marzo and A. Merkoçi, Lab Chip, 2016, 16, 3150 DOI: 10.1039/C6LC00737F

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