Issue 40, 2016

A mesoporous organosilica nano-bowl with high DNA loading capacity – a potential gene delivery carrier

Abstract

Mesoporous organosilica nanoparticles with a novel bowl-like morphology were synthesized. These nano-bowls possess uniform particle sizes around 180 nm and open cavities around 140 nm, which lead to higher loading capability for plasmid DNA than traditional silica-based nanoparticles. In vitro DNA transfection using these nano-bowls is demonstrated.

Graphical abstract: A mesoporous organosilica nano-bowl with high DNA loading capacity – a potential gene delivery carrier

Supplementary files

Article information

Article type
Communication
Submitted
26 Aug 2016
Accepted
19 Sep 2016
First published
20 Sep 2016

Nanoscale, 2016,8, 17446-17450

A mesoporous organosilica nano-bowl with high DNA loading capacity – a potential gene delivery carrier

L. Xiong and S. Qiao, Nanoscale, 2016, 8, 17446 DOI: 10.1039/C6NR06777H

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