SCHEDULED MAINTENANCE
A chiral phosphoric acid-catalyzed asymmetric transfer hydrogenation of 3-trifluoromethylthioquinolines has been successfully developed, providing direct and facile access to chiral 2,3-disubstituted 1,2,3,4-tetrahydroquinoline derivatives containing a stereogenic trifluoromethylthio group with up to 99% enantioselectivity.
J. Zhou, Q. Zhang, W. Zhao and G. Jiang, Org. Biomol. Chem., 2016, 14, 6937 DOI: 10.1039/C6OB01176D
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