Issue 4, 2017

Carboxylatopillar[n]arenes: a versatile class of water soluble synthetic receptors

Abstract

Carboxylatopillar[n]arenes (CP[n]As, n = 5, 6, 7, 9, 10) are water soluble derivatives of pillar[n]arenes. The three-dimensional π-electron-rich cavity and carboxylate groups at the portals, enabled CP[n]A to have strong binding affinity in water, which has been successfully harnessed in fabricating responsive supramolecular assemblies from supra-amphiphiles and developing targeted drug delivery systems (DDSs). CP[n]A based supraamphiphiles have also been used for sensor applications. This review highlights the diverse applications of water soluble carboxylatopillar[n]arenes.

Graphical abstract: Carboxylatopillar[n]arenes: a versatile class of water soluble synthetic receptors

Article information

Article type
Review Article
Submitted
11 Oct 2016
Accepted
02 Dec 2016
First published
02 Dec 2016

Org. Biomol. Chem., 2017,15, 762-772

Carboxylatopillar[n]arenes: a versatile class of water soluble synthetic receptors

S. Dasgupta and P. S. Mukherjee, Org. Biomol. Chem., 2017, 15, 762 DOI: 10.1039/C6OB02214F

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