Issue 13, 2016
From the journal:

Polymer Chemistry

Self-assembled fluorodendrimers in the co-delivery of fluorinated drugs and therapeutic genes†

Hui Wang,ab   Jingjing Hu,a   Xiaopan Cai,b   Jianru Xiao*b  and  Yiyun Cheng*a  

* Corresponding authors

a Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, P. R. China
E-mail: yycheng@mail.ustc.edu.cn

b Changzheng Hospital, Department of Orthopedic Oncology, Shanghai, P.R. China
E-mail: jianruxiao@163.com

Abstract

Fluorinated drugs now make up about 25% of all pharmaceuticals. However, versatile carriers are currently lacking for the delivery of fluorinated drugs. Here, we developed a fluorodendrimer as a versatile and multifunctional carrier for fluorinated drugs. The fluorodendrimer enables the co-delivery of fluorinated anticancer drugs and therapeutic genes for synergistic cancer therapy.

Graphical abstract: Self-assembled fluorodendrimers in the co-delivery of fluorinated drugs and therapeutic genes

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Article information

DOI
https://doi.org/10.1039/C6PY00153J
Article type
Communication
Submitted
28 Jan 2016
Accepted
25 Feb 2016
First published
25 Feb 2016

Polym. Chem., 2016,7, 2319-2322

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Self-assembled fluorodendrimers in the co-delivery of fluorinated drugs and therapeutic genes

H. Wang, J. Hu, X. Cai, J. Xiao and Y. Cheng, Polym. Chem., 2016, 7, 2319 DOI: 10.1039/C6PY00153J

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