Issue 2, 2017

Rh(iii)-Catalyzed direct C-7 amination of indolines with anthranils

Abstract

An efficient and practical method for the C-7 amination of indolines via Rh(III)-catalyzed C–H activation has been reported. This reaction affords various C-7 aminated indolines in good to excellent yields by using readily available anthranils as the aminating agents. The corresponding indolines with an amino and a carbonyl group together provide an opportunity for the construction and modification of diverse indoles and indolines in the pharmaceutical industry.

Graphical abstract: Rh(iii)-Catalyzed direct C-7 amination of indolines with anthranils

Supplementary files

Article information

Article type
Research Article
Submitted
14 Nov 2016
Accepted
05 Dec 2016
First published
06 Dec 2016

Org. Chem. Front., 2017,4, 250-254

Rh(III)-Catalyzed direct C-7 amination of indolines with anthranils

H. Li, J. Jie, S. Wu, X. Yang and H. Xu, Org. Chem. Front., 2017, 4, 250 DOI: 10.1039/C6QO00709K

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