Copper-catalyzed carbonylation of anilines by diisopropyl azodicarboxylate for the synthesis of carbamates

Abstract

A Cu-catalyzed efficient methodology for the direct carbonylation of anilines has been developed. The N–H bond cleavage and N–C bond formation were notably achieved under solvent-free conditions and a variety of carbamates were synthesized from readily available anilines using diisopropyl azodicarboxylate (DIAD) as the carbonylating source.