Issue 24, 2017, Issue in Progress

A glassy carbon electrode modified with γ-Ce2S3-decorated CNT nanocomposites for uric acid sensor development: a real sample analysis

Abstract

γ-Ce2S3-decorated multi-walled carbon nanotube nanocomposite (Ce2S3-CNT NC) was synthesized by a wet chemical method in basic phase. Characterization of the resulting Ce2S3-CNT NCs was performed in detail by field emission scanning electron microscopy (FE-SEM) attached with energy dispersive spectroscopy (EDS), X-ray photoelectron spectroscopy (XPS), UV/vis spectroscopy, FT-IR spectroscopy, and X-ray diffraction (XRD). A glassy carbon electrode (GCE) was fabricated using the Ce2S3-CNT NCs and then it was utilized to develop a biological sensor for the detection of uric acid (UA) via a simple electrochemical approach. With the selectivity study, UA was selected as a target since it exhibited a fast response towards the Ce2S3-CNT NC-fabricated GCE sensor in the IV method. The fabricated sensor also displayed an excellent sensitivity, very low detection limit, long-term stability, and reproducibility. In the diagnostic study, a linear calibration plot (r2 = 0.9972) was obtained for 0.1 nM to 1.0 mM aqueous UA solution, with the sensitivity value of 1.5822 μA nM−1 m−2 and an extremely low detection limit LOD = 60.0 ± 0.05 pM (S/N = 3). Potentials of the Ce2S3-CNT NCs in terms of biological sensing were also investigated via real serum and urine sample analyses. This approach is emerging as an effective technique in the development of an efficient biological sensor for the detection of biochemicals in broad scales.

Graphical abstract: A glassy carbon electrode modified with γ-Ce2S3-decorated CNT nanocomposites for uric acid sensor development: a real sample analysis

Supplementary files

Article information

Article type
Paper
Submitted
27 Nov 2016
Accepted
21 Feb 2017
First published
06 Mar 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 14649-14659

A glassy carbon electrode modified with γ-Ce2S3-decorated CNT nanocomposites for uric acid sensor development: a real sample analysis

M. M. Rahman, J. Ahmed and A. M. Asiri, RSC Adv., 2017, 7, 14649 DOI: 10.1039/C6RA27414E

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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